Moses Mbye is fit to play after a scare in the Maroons camp last Friday and is likely to remain in the centres.
Adam Reynolds (back) and Braidon Burns (hamstring) are expected to return from injury, while Origin trio Damien Cook, Dane Gagai and Cameron Murray could be rested.
Tyson Frizell could miss with a neck injury, while Origin trio Ben Hunt, Paul Vaughan and Tariq Sims are expected to be available.
Scott Drinkwater looks set to play his first game for the Cowboys after crossing from the Storm. Josh McGuire was hit with a one-game suspension and Michael Morgan (shoulder) and Kurt Baptiste (knee) will also miss.
All 10 of the Roosters' Representative players are healthy and available for selection. Luke Keary is nearing a return.
The Storm has added Max King and Solomone Kata to its squad this week and upgraded Harry Grant.
Origin players Will Chambers, Josh Addo-Carr, Dale Finucane, Felise Kaufusi, and Cameron Munster are all expected to be available.
Ash Taylor (personal issues) is unlikely and Jai Arrow (ankle) should miss the next two weeks, but Moeaki Fotuaika (wrist) is firming for a return.
Origin trio Daly Cherry-Evans, Jake Trbojevic, and Tom Trbojevic should all be named.
Tim Glasby (elbow), Kalyn Ponga (cork) are both in doubt, while Danny Levi (ankle) will miss. Mitchell Pearce (hip) and Edrick Lee (leg) should both be available, while David Klemmer (wrist) is a chance.
Joe Ofahengaue is confident of making a shock return from a bad leg injury in Origin I, while Payne Haas (hamstring) could also return despite missing Origin II.
Dylan Brown (back) could return and Blake Ferguson should be available.
Josh Hodgson (thumb) is set to return, along with Charnze Nicoll-Klokstad (hamstring) and Corey Horsburgh(elbow). Nick Cotric (ankle) will miss another week but Origin duo Jack Wighton and Josh Papalii should be good to go.
Nathan Roache (back) is a question mark, but Tohu Harris should be available.
Nathan Cleary (ankle) is set for a month on the sidelines, while James Maloney will be good to go. Jarome Luai should move into the halves and Josh Mansour is also set to play.
Dylan Napa (wrist) is likely to rest in this one in a bid to be available for Origin III.
Andrew Fifita is facing a three-match suspension, while Wade Graham is available.