Entering Round 5, some NRL clubs are set to receive significant boosts to their team, while others have lost key players as they look to clinch the two points.
Some big additions this week include Cameron Munster, Alex Twal and Jahrome Hughes, while the losses are headlined by Jacob Preston and Luke Metcalf.
Teams will be named on Tuesday at 4pm (AEST), but here is all the latest in news and rumours.
Manly Sea Eagles vs Penrith Panthers
Despite losing against the St George Illawarra Dragons in Round 4, it is hard to see the club make any changes to the team after not missing anyone to injuries or suspension.
Anthony Seilbold revealed that Josh Schuster will remain in the NSW Cup for the time being and will not be called-up to the side this weekend.
Project Round 5 Team: 1. Tom Trbojevic 2. Tommy Talau 3. Tolutau Koula 4. Reuben Garrick 5. Jaxson Paulo 6. Luke Brooks 7. Daly Cherry-Evans 8. Taniela Paseka 9. Lachlan Croker 10. Josh Aloiai 11. Haumole Olakau'atu 12. Ben Trbojevic 13. Jake Trbojevic 14. Karl Lawton 15. Corey Waddell 16. Toafofoa Sipley 17. Nathan Brown
Nathan Cleary has confirmed that he won't return to after the bye in Round 7 meaning the Panthers will roll out the same team as last week's victory over the Sydney Roosters.
Scott Sorensen and James Fisher-Harris remain injured and won't be rushed back, with the latter likely to return at the same time as his star halfback.
Projected Round 5 Team: 1. Dylan Edwards 2. Sunia Turuva 3. Izack Tago 4. Taylan May 5. Brian To'o 6. Jarome Luai 7. Brad Schneider 8. Moses Leota 9. Mitch Kenny 10. Lindsay Smith 11. Luke Garner 12. Liam Martin 13. Isaah Yeo 14. Daine Laurie 15. Mavrik Geyer 16. Liam Henry 17. Matthew Eisenhuth
