Manly will be without Brad Parker and Curtis Sironen for their clash with the Tigers this weekend, after the pair suffered injuries in the Sea Eagles' loss to the Warriors on Friday night.
Parker suffered a knee injury and has damaged the cartilage in his knee, while Sironen has a hamstring strain.
The pair could both miss up to two weeks, but have been ruled out for Thursday night's match at Lottoland.
Skipper Daly Cherry-Evans is set to be named on Tuesday, after pulling up okay despite ankle concerns from the Warriors game.